Translational Brain Research Program

Upcoming event June 13, 2019

Symposium NeuroPlatform Kempenhaeghe Congress
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NeuroPlatform is a multidisciplinary brain research program involving academic and commercial partners from both the Netherlands and Belgium. We combine technical and medical expertise to get the most out of our research, and carry out joint projects around topics of Neurology, Neuropsychiatry, and Ageing and vulnerable patients (see the matrix below). Our technical challenges are Neuromodulation, Neuroimaging and Monitoring (EEG and sensoring).


Neurological and neuropsychiatric impairments have a high incidence and prevalence. When also taking vulnerable groups into account such as patients with pathological ageing, 1 out of 4 people in the Netherlands have brain disorders (Hersenstichting Nederland).
Several challenges exists in this area, specifically diagnostic challenges (e.g. poor reproducibility of questionnaires for diagnosis of autism), treatment navigation challenges (e.g. when to apply which treatment in depression) and treatment challenges (e.g. failure of pharmacotherapy in epilepsy). For some of the brain conditions no treatment at all is available such as in neurodegenerative diseases (e.g. Alzheimer).


Our approach is based on the assumption that technological solutions are possible for the described clinical challenges and that close collaboration between technical and clinical partners is essential to keep our research as relevant and aligned with clinical needs as possible. This dual approach (technical/clinical) is apparent at all levels of our team (management, scientific supervision, PhD students).

Matrix of the medical/clinical and technical challenges addressed in the NeuroPlatform:

Neurology (e.g. epilepsy, stroke) Neurolopsychiatry (e.g. depression, autism) Ageing and vulnerable groups
Neuromodulation (including invasive and non-invasive neurostimulation)
Multimodal MRI
Monitoring (including high-density EEG and intelligent sensoring)

Neurofeedback is the concept of making someone aware of his own neuronal activity. The idea is that by making someone aware of his mental state, he may learn how to control or modify this. fMRI neurofeedback typically involves monitoring the activity in a certain region-of-interest. Within the Neu3CA program, we are developing fMRI neurofeedback for (complete) neuronal networks, with the aim of treating cognitive impairments.

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EEG (elecotro-encephalograpy) provides a direct window on neuronal activity: it captures the rapid changes in electical fields generated by neuronal firing. In this project, we combine EEG data with data-mining techniques and graph theory to find EEG-markers of neurological diseases.

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Epilepsy may have a large varierty of causes, amongst others is may develop after a stroke. Within this project, we study post-stroke epilepsy using high field (7T) MRI.

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René was a speaker at the SUMMA student symposium in Utrecht.

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In the March 2017 edition of the Dutch Epilepsy Foundation's Epilepsy Magazine, the launch of the Neu3CA research program was reported.

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Bert Aldenkamp

senior investigator and founding father, KH, Maastricht UMC, TU/e, UZ Gent

Paul Boon

senior investigator and founding father, UZ Gent, U Gent, KH, TU/e

Jan Bergmans

senior investigator and founding father, TU/e, KH, Philips Research

Anton Tijhuis

senior investigator and founding father, TU/e

Kristl Vonck

senior investigator, U Gent, UZ Gent

Mykola Pechenizkiy

professor, TU/e

Evelien Carrette

clinical program director, UZ Gent, U Gent, TU/e, KH

Rob Mestrom

researcher, PhD supervisor, TU/e

Sveta Zinger

assistant professor, TU/e

Anton de Louw

researcher, PhD supervisor, KH, TU/e

Marcel Breeuwer

professor and principal scientist, TU/e, Philips Healthcare

Rob Rouhl

assistant professor, Maastricht UMC

Jaap Jansen

assistant professor, MUMC

Antoine Bernas

PhD candidate, TU/e

Debby Klooster

PhD candidate, TU/e, KH, UZ Gent

Elles Raaijmakers

PhD candidate, TU/e

Maarten van Rossum

PhD candidate, TU/e

Lisanne Breuer

PhD candidate, KH

Edo Grevers

PhD candidate, KH

Gerald Drenthen

PhD candidate, Maastricht UMC

Sofie Carrette

PhD candidate, UZ Gent, U Gent

Negar Ahmadi

PhD candidate, TU/e

Charlotte Germonpré

PhD candidate, U Gent

Lisanne Canjels

PhD candidate, MUMC

Stephan Heunis

PhD candidate, TU/e

Chris Baeken

affiliate, principal investigator, U Gent

Regina Luttge

affiliate, TU/e

Peter H. N. de With

affiliate, TU/e

Govert Hoogland

affiliate, Maastricht University

Wytse Wadman

affiliate, University of Amsterdam, U Gent

Robrecht Raedt

affiliate, U Gent

Marijke Miatton

affiliate, UZ Gent

Veerle de Herdt

affiliate, UZ Gent

Rolf Lamerichs

senior investigator, Philips Research

Maarten Versluis

affiliate, Philips Healthcare

Marco Matters

affiliate, Philips Research

Marieke van der Hoeven

affiliate, Philips Research

Radu Jasinschi

affiliate, Philips Research

All members